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Several Drug Rehabilitation Center in Mumbai stated that the oral route of drug administration is the most important method of administering drugs for systemic effects. The Drug Rehabilitation Center in Mumbai mainly defined Tablets as a definition of a compressed unit solid dosage form containing medicaments with or without excipients. Excipients may include diluents ,binders, granulating agents, glidants and lubricants to ensure the systematic process of tableting. The Drug Rehabilitation Center in Mumbai mainly says that not all tablets are good for body consumption, and many-a-times people consume them just to stay dozed off. Thus, below are the advantages and disadvantages of tablets.
Advantages of Tablets 1) They are a unit dose form, they offer the greatest capabilities of all oral forms for the greatest dose precision and the least content variability. 2) Their cost is the lowest. 3) They are the lightest and the most dense of all oral dosage forms. 4) They are the easiest and cheapest to package and ship. 5) Product identification is simple and cheap. 6)They provide the greatest ease to swallow. 7) They impart themselves to certain special release profile products, such as enteric or delayed release products. 8) They are better suited for large scale production. Disadvantages of Tablets 1) Some medicines withstand compression into dense compacts, owing to their amorphous nature,low density character. 2) Drugs with poor wetting, slow dissolution properties, intermediate to larger dosages may cause difficulty, or not possible to formulate and manufacture as a tablet that will still provide adequate or full drug bioavailability. 3) Bitter tasting drugs drugs with objectionable odor, that are sensitive to oxygen required encapsulation prior to compression or tablets may require coating. Evaluation1) General Appearance-It contains visual identity and overall "elegance" is most important for consumer's perspective, lot-to-lot uniformity and general tablet -to-tablet uniformity. 2)Size and Shape-Tablet thickness should be controlled within a plus and minus 5% variation of a standard value. 3)Unique Identification Marking- It includes the company name or symbol,a product code such as that from the NDC(National Drug Code) number, the product name or the product potency 4)Organoleptic Properties-Pharmaceutical tablets use color as a vital means of rapid identification and consumer acceptance. 5)Hardness and Friability-Hardness means the tablet crushing strength.The testers for evaluation of tablet hardness was the Mansanto hardness tester. The friability tester is known as Roche Friabilitor. The misuse of medicines is a crucial global problem. Irrational usage of medicines and drugs has led to wastage of resources and most importantly evolution of susceptible pathogens to antibiotic-resistant ‘superbugs’. Due to this situation, the urge to discover and develop safe and efficient anti-microbial substances has arisen to cure lethal diseases. But do you know, to create or discover an antibiotic or antimicrobial drug and to sell it in a safe & consumable form in the market takes approximately a decade or even more. Due to this and with rising types and numbers of diseases, we are losing the battle between illness and life. The Alcohol Rehabilitation Center in India have thus raised the debates about whether alcohol is good for us or not have been going on for a while, and what we know for certain is that if drank in moderation, it certainly won't do you any harm. However, not only will it not be bad for you, but it can actually contribute to lowering the risk of several major illnesses as well as prolong your life. However, the Alcohol Rehabilitation Center in India also said that ‘Moderation is the key’, and if you like to indulge in a glass or two of whiskey a day, or you indulge a glass of wine over dinner, it will have a plethora of benefits for your health. Let’s see the effects of a little wine according to the Alcohol Rehabilitation Center in India.
Protects against diabetes According to a study published in the journal Diabetologia, having a glass or two of wine every few days may help protect against type 2 diabetes. As the study showed, those who drank three to four days a week had a 30% less chance of developing diabetes unlike those who drank less than once a week. One of the possible reasons for this is the polyphenol compounds in red wine which are likely to help manage blood sugar levels and keep them in check. Whiskey reduces stress Have you ever been in a stressful situation where you just had to have a sip of something strong to take the edge off? If not, you should know for future reference that only one serving of whiskey can settle the nerves and calm the brain. To understand all the peculiarities about whiskey, it would be a good idea if you started learning more about the process of making it. To do that, you can book a whiskey tour and observe how whiskey is made and hear all about the process through which it goes on its way to being bottled. Wine is healthy for the heart According to a study, people who did not drink wine were at a higher risk (12% to 65%) of eight heart ailments, unlike those who drank in moderation. Heart attack, stroke and sudden heart-related death were only some of the eight conditions. Non-drinkers had a 33% more chance of unstable angina and a 56% more chance of dying unexpectedly from heart disease. Therefore, a glass or two of wine a day is likely to protect you from serious heart conditions. Beer prolongs life Aside from wine and whiskey, beer can also be beneficial for your well-being. Having a pint or two a day could help reduce the risk of having a stroke. According to research conducted among Chinese adults, a moderate daily beer intake slows down the decline of high-density lipoprotein (HDL), or "good" cholesterol, which is one of the best ways to prevent stroke. So, if you’ve been thinking about giving up your daily dose of beer, think again. It’s actually good for you. Final thoughts If you’ve been worried about jeopardizing your health by occasionally indulging in a glass of whiskey or wine, you can finally have peace of mind. As long as you’re drinking in moderation and not ending up hungover the next morning, not only will your body be alright, but it will potentially prevent various chronic illnesses. The Alcohol Rehabilitation Center in India states that for most grown-ups, moderate liquor use is presumably not hurtful. Nonetheless, around 18 million grown-up Americans have a liquor use issue (AUD). This implies their drinking causes pain and damage. It incorporates liquor addiction and liquor misuse. Liquor addiction, or liquor reliance, is an infection that causesDesiring - a solid need to drink Loss of control - not having the option to quit drinking once you've begun Physical reliance - withdrawal side effects Resistance - the need to drink more liquor to feel a similar impact With liquor misuse, you are not physically needy, yet regardless you have a major issue. Drinking may cause issues at home, work, or school. It might make you place yourself in hazardous circumstances, or lead to lawful or social issues. Another regular issue is hitting the bottle hard. It is drinking around at least five beverages in two hours for men. For ladies, it is around at least four beverages in two hours. The Alcohol Rehabilitation Center in India says that a lot of liquor is perilous. Substantial drinking can expand the danger of specific tumors. It can harm the liver, cerebrum, and different organs. Drinking during pregnancy can hurt your infant. The Alcohol Rehabilitation Center in India says that Liquor additionally builds the danger of death from vehicle crashes, wounds, murder, and suicide. Avoid, or at least reduce, your consumption of nicotine and any drinks containing caffeine and alcohol. Caffeine and nicotine are stimulants and so will increase your level of stress rather than reduce it. Alcohol is a depressant when taken in large quantities, but acts as a stimulant in smaller quantities. Therefore using alcohol as a way to alleviate stress is not ultimately helpful. Swap caffeinated and alcoholic drinks for water, herbal teas, or diluted natural fruit juices and aim to keep yourself hydrated as this will enable your body to cope better with stress. You should also aim to avoid or reduce your intake of refined sugars - they are contained in many manufactured foods (even in savoury foods such as salad dressings and bread) and can cause energy crashes which may lead you to feel tired and irritable. In general, try to eat a healthy, well-balanced and nutritious diet. Stressful situations increase the level of stress hormones such as adrenaline and cortisol in your body. These are the “fight or flight” hormones that evolution has hard-wired into our brains and which are designed to protect us from immediate bodily harm when we are under threat. However, stress in the modern age is rarely remedied by a fight or flight response, and so physical exercise can be used as a surrogate to metabolize the excessive stress hormones and restore your body and mind to a calmer, more relaxed state. When you feel stressed and tense, go for a brisk walk in fresh air. Try to incorporate some physical activity into your daily routine on a regular basis, either before or after work, or at lunchtime. Regular physical activity will also improve the quality of your sleep. |
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March 2022
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